The medial superior genicular artery is one of several blood vessels that supply the knee-joint region. It springs directly from the popliteal artery. Then it travels medially and forwards under the tendon of the semimembranosus and adductor magnum muscle right above the medial condyle of femur.
It curves around the medial surface of this bone, sending smaller branches as it goes. There, the medial superior genicular artery anastomoses with other secondary arterial branches, such as the middle genicular and the sural arteries, thus contributing to the formation of the network of arteries that supply the knee (muscles, tendons, ligament, and bones).
Below a schematic drawing portraying the arteries of the knee-joint region, posterior aspect. The medial superior genicular is marked on the left side of image, right below the popliteal a.